Wrentham
- Address: I-495 and I-95
- Vicinity: NW of I-495 and I-95
- US County of Norfolk County, MA in Massachusetts
Wrentham, 25 mi SW of Boston, was settled in 1660 and incorporated in 1673. The village was a favorite of Helen Keller, American author and advocate. In her autobiography, The Story of My Life, she mentions spending time 'with our friends, the Chamberlins' and of Wrentham as 'one of the most charming villages in New England.'