The significance of the Jedediah Higgins House lies with it being representative of the 19th century version of a Cape Cod house architectural style which originated in basic form in the late 17th century and is still a prominent architectural style on Cape Cod today.

The primary features which make this house an important example of this architectural type are its central facade, floor plan, and interior finishes. The basically intact and unaltered central facade typifies a Cape Cod double-house with its south orientation and its symmetrical placement of two windows on either side of a central front doorway. Similarly, the floor plan with its arrangement of a central entrance flanked by two south rooms and a north room around a central chimney, and bedrooms upstairs is typical for a Cape Cod house and is basically intact. Likewise, the interior of the house with its wood paneling, wainscoting, and wide floor boards is basically unaltered from its 19th century origins and typifies the architectural style of interior finishes during that era. - NRHP, 21 November 1984