The Colorado Plateau has sharply defined boundaries that separate it from neighboring geomorphic provinces. On the west, faults and the perimeters of volcanic plateaus mark the boundary between the Colorado Plateau and the Basin and Range Province. The boundary extends across the southern edge of the plateau where it is less radically defined, but is nonetheless visible on the surface in the form of an uplifted edge of sedimentary rocks known as the Mogollon Rim, which extends from northwest Arizona diagonally into north-central New Mexico. The eastern and northern boundaries are delineated by the contact between sedimentary rocks and upthrust or folded crystalline rocks of the Rocky Mountains.

The plateau is a definable tectonic unit relatively easily separated from other provinces, but it shows considerable internal variation. The interior of the kidney-shaped Colorado Plateau Province reveals a series of subsections that depend on geologic and geomorphologic definition. The centrally located Canyon Lands Section is dominated by gently folded sedimentary rocks, while the western High Plateaus Section reveals widespread accumulations of volcanic materials. - USGS